Dose Reduction

  I had to have a dose reduction starting today due to my peripheral neuropathy symptoms. My toes are numb yet painful and my fingers have intermittent numbness with difficulty performing fine motor tasks (think buttons, zippers, ketchup packets, etc). I’m considered a grade 2 at this time. I didn’t know there were grades until now. Don’t ignore your peripheral neuropathy symptoms. Tell your doctor what you’re experiencing so they can make the best call on your treatment. 

According to the WHO rating scale:

• Grade 0 corresponds to no symptoms of neuropathy
• Grade 1 corresponds to paresthesias (a tingling, tickling or prickling sensation) and/or decreased tendon reflexes
• Grade 2 corresponds to severe paresthesias and/or mild weakness
• Grade 3 corresponds to intolerable paresthesias and/or marked motor loss
• Grade 4 corresponds to paralysis.